A Reduction of Cyclooxygenase 2 Gene Dosage Counters the Ovarian Morphological Aging and Tumor Phenotype in Wv Mice

Menopausal ovaries undergo morphological changes, known as ovarian aging, which are implicated in the high incidence of ovarian cancer occurring during the perimenopausal and immediate postmenopausal periods. The germ cell-deficient Wv mice recapitulate these postmenopausal alterations in ovarian mo...

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Autors principals: Yang, Wan-Lin, Cai, Kathy Qi, Smedberg, Jennifer L., Smith, Elizabeth R., Klein-Szanto, Andres, Hamilton, Thomas C., Xu, Xiang-Xi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2007
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829465/
https://ncbi.nlm.nih.gov/pubmed/17392171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060769
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