A Reduction of Cyclooxygenase 2 Gene Dosage Counters the Ovarian Morphological Aging and Tumor Phenotype in Wv Mice

Menopausal ovaries undergo morphological changes, known as ovarian aging, which are implicated in the high incidence of ovarian cancer occurring during the perimenopausal and immediate postmenopausal periods. The germ cell-deficient Wv mice recapitulate these postmenopausal alterations in ovarian mo...

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Detalhes bibliográficos
Main Authors: Yang, Wan-Lin, Cai, Kathy Qi, Smedberg, Jennifer L., Smith, Elizabeth R., Klein-Szanto, Andres, Hamilton, Thomas C., Xu, Xiang-Xi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829465/
https://ncbi.nlm.nih.gov/pubmed/17392171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060769
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