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Efficient Route to C(2) Symmetric Heterocyclic Backbone Modified Cyclic Peptides

[Image: see text] A tandem dimerization–macrocyclization approach using 1,3-dipolar azide–alkyne cycloaddition reactions has been employed in the facile and convergent solution phase syntheses of C(2) symmetric cyclic peptide scaffolds bearing triazole ε2-amino acids as dipeptide surrogates.

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Detaylı Bibliyografya
Asıl Yazarlar: van Maarseveen, Jan H., Horne, W. Seth, Ghadiri, M. Reza
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829324/
https://ncbi.nlm.nih.gov/pubmed/16178569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0518028
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