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Efficient Route to C(2) Symmetric Heterocyclic Backbone Modified Cyclic Peptides
[Image: see text] A tandem dimerization–macrocyclization approach using 1,3-dipolar azide–alkyne cycloaddition reactions has been employed in the facile and convergent solution phase syntheses of C(2) symmetric cyclic peptide scaffolds bearing triazole ε2-amino acids as dipeptide surrogates.
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1829324/ https://ncbi.nlm.nih.gov/pubmed/16178569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0518028 |
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