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On the thermodynamic stability of a charged arginine side chain in a transmembrane helix

Biological membranes consist of bilayer arrangements of lipids forming a hydrophobic core that presents a physical barrier to all polar and charged molecules. This long-held notion has recently been challenged by biological translocon-based experiments that report small apparent free energies to ins...

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Autori principali: Dorairaj, Sudha, Allen, Toby W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829244/
https://ncbi.nlm.nih.gov/pubmed/17360368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610470104
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