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Role of Side-Chain Conformational Entropy in Transmembrane Helix Dimerization of Glycophorin A

Dimerization of the transmembrane domain of glycophorin A is mediated by a seven residue motif LIxxGVxxGVxxT through a combination of van der Waals and hydrogen bonding interactions. One of the unusual features of the motif is the large number of β-branched amino acids that may limit the entropic co...

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Autori principali: Liu, Wei, Crocker, Evan, Siminovitch, David J., Smith, Steven O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302702/
https://ncbi.nlm.nih.gov/pubmed/12547806
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