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Convergent chemical synthesis and high-resolution x-ray structure of human lysozyme

In this article, we report the total chemical synthesis of human lysozyme. Lysozyme serves as a widespread model system in various fields of biochemical research, including protein folding, enzyme catalysis, and amyloidogenesis. The 130-aa wild-type polypeptide chain of the human enzyme was assemble...

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Bibliographic Details
Main Authors: Durek, Thomas, Torbeev, Vladimir Yu., Kent, Stephen B. H.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829227/
https://ncbi.nlm.nih.gov/pubmed/17360367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610630104
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