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De Novo Sphingolipid Synthesis Is Essential for Viability, but Not for Transport of Glycosylphosphatidylinositol-Anchored Proteins, in African Trypanosomes

De novo sphingolipid synthesis is required for the exit of glycosylphosphatidylinositol (GPI)-anchored membrane proteins from the endoplasmic reticulum in yeast. Using a pharmacological approach, we test the generality of this phenomenon by analyzing the transport of GPI-anchored cargo in widely div...

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Hlavní autoři: Sutterwala, Shaheen S., Creswell, Caleb H., Sanyal, Sumana, Menon, Anant K., Bangs, James D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828920/
https://ncbi.nlm.nih.gov/pubmed/17220466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00283-06
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