Reduction of Worm Fecundity and Canine Host Blood Loss Mediates Protection against Hookworm Infection Elicited by Vaccination with Recombinant Ac-16

Hookworm infection is one of most important parasitic infection of humans, occurring in 740 million people. Here we report the protective vaccination of dogs with Ac-16, an immunodominant surface antigen from the hookworm Ancylostoma caninum. We show that immunization with Ac-16 formulated with AS03...

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Auteurs principaux: Fujiwara, Ricardo T., Zhan, Bin, Mendez, Susana, Loukas, Alex, Bueno, Lilian L., Wang, Yan, Plieskatt, Jordan, Oksov, Yelena, Lustigman, Sara, Bottazzi, Maria Elena, Hotez, Peter, Bethony, Jeffrey M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Veterinary Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828853/
https://ncbi.nlm.nih.gov/pubmed/17267592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00404-06
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