Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation

A 5-week-old male infant presented with severe bacterial infections and poor wound healing, suggesting a neutrophil defect. Neutrophils from this patient exhibited decreased chemotaxis, polarization, azurophilic granule secretion, and superoxide anion (O(2)(−)) production but had normal expression a...

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Détails bibliographiques
Auteurs principaux: Ambruso, Daniel R., Knall, Cindy, Abell, Amy N., Panepinto, Julie, Kurkchubasche, Arlet, Thurman, Gail, Gonzalez-Aller, Carolina, Hiester, Andrew, deBoer, Martin, Harbeck, Ronald J., Oyer, Ryan, Johnson, Gary L., Roos, Dirk
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2000
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC18288/
https://ncbi.nlm.nih.gov/pubmed/10758162
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