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Changing a Single Amino Acid in Clostridium perfringens β-Toxin Affects the Efficiency of Heterologous Secretion by Bacillus subtilis

Achieving efficient heterologous protein production and secretion by Bacillus subtilis is an attractive prospect, although often disappointingly low yields are reached. The expression of detoxified Clostridium perfringens β-toxin (β-toxoid) is exemplary for this. Although β-toxin can be efficiently...

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Main Authors: Nijland, Reindert, Heerlien, René, Hamoen, Leendert W., Kuipers, Oscar P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828759/
https://ncbi.nlm.nih.gov/pubmed/17209068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02356-06
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