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Changing a Single Amino Acid in Clostridium perfringens β-Toxin Affects the Efficiency of Heterologous Secretion by Bacillus subtilis

Achieving efficient heterologous protein production and secretion by Bacillus subtilis is an attractive prospect, although often disappointingly low yields are reached. The expression of detoxified Clostridium perfringens β-toxin (β-toxoid) is exemplary for this. Although β-toxin can be efficiently...

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Bibliographische Detailangaben
Hauptverfasser: Nijland, Reindert, Heerlien, René, Hamoen, Leendert W., Kuipers, Oscar P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828759/
https://ncbi.nlm.nih.gov/pubmed/17209068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02356-06
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