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Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry assay for organophosphorus toxicants bound to human albumin at Tyr411
Our goal was to determine whether chlorpyrifos oxon, dichlorvos, diisopropylfluorophosphate (DFP), and sarin covalently bind to human albumin. Human albumin or plasma was treated with organophosphorus agent (OP) at alkaline pH, digested with pepsin at pH 2.3, and analyzed by MADLI-TOF mass spectrome...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1828685/ https://ncbi.nlm.nih.gov/pubmed/17188226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2006.11.018 |
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