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CHARACTERIZATION OF GLYCATION ADDUCTS ON HUMAN SERUM ALBUMIN BY MATRIX ASSISTED LASER DESORPTION/IONIZATION TIME-OF-FLIGHT MASS SPECTROMETRY

BACKGROUND: Non-enzymatic glycation of human serum albumin (HSA) is associated with the long-term complications of diabetes. We examined the structure and location of modifications on minimally glycated HSA and considered their possible impact on the binding of drugs to this protein. METHODS: Minima...

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Detalhes bibliográficos
Main Authors: Wa, Chunling, Cerny, Ronald L., Clarke, William A., Hage, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692699/
https://ncbi.nlm.nih.gov/pubmed/17707360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2007.06.011
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