Cellular Pyrin Domain-Only Protein 2 Is a Candidate Regulator of Inflammasome Activation

Pyrin domain (PYD) proteins have recently emerged as important signaling molecules involved in the development of innate immunity against intracellular pathogens through activation of inflammatory mediator pathways. ASC is the central adaptor protein, which links pathogen recognition by PYD-containi...

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Main Authors: Dorfleutner, Andrea, Bryan, Nicole B., Talbott, Siera J., Funya, Kristin N., Rellick, Stephanie L., Reed, John C., Shi, Xianglin, Rojanasakul, Yon, Flynn, Daniel C., Stehlik, Christian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828547/
https://ncbi.nlm.nih.gov/pubmed/17178784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01315-06
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