Heterologous Priming-Boosting with DNA and Modified Vaccinia Virus Ankara Expressing Tryparedoxin Peroxidase Promotes Long-Term Memory against Leishmania major in Susceptible BALB/c Mice

Leishmaniasis affects 12 million people, but there are no vaccines in routine clinical use. Th1 polarizing vaccines that elicit long-term protection are required to prevent disease in susceptible populations. We recently showed that heterologous priming-boosting with tryparedoxin peroxidase (TRYP) D...

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Hlavní autoři: Stober, Carmel B., Lange, Uta G., Roberts, Mark T. M., Alcami, Antonio, Blackwell, Jenefer M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Fungal and Parasitic Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828487/
https://ncbi.nlm.nih.gov/pubmed/17101647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01490-06
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