Interleukin-4 (IL-4) and IL-10 Collude in Vaccine Failure for Novel Exacerbatory Antigens in Murine Leishmania major Infection

Leishmaniasis affects 12 million people but there are no vaccines in routine use. Recently, we used DNA vaccination in a susceptible BALB/c high-dose model of infection to screen 100 novel Leishmania major genes as vaccine candidates. In addition to finding novel protective antigens, we identified s...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Roberts, Mark T. M., Stober, Carmel B., McKenzie, Andrew N, Blackwell, Jenefer M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2005
Ämnen:
Fungal and Parasitic Infections
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1273906/
https://ncbi.nlm.nih.gov/pubmed/16239566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.11.7620-7628.2005
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk