Interleukin-4 (IL-4) and IL-13 Suppress Excessive Neutrophil Infiltration and Hepatocyte Damage during Acute Murine Schistosomiasis Japonica

Due to the importance of neutrophils and proinflammatory cytokines in schistosomal liver damage, we analyzed the mechanisms underlying neutrophil and proinflammatory responses in murine schistosomiasis japonica. We found that granulomatous inflammation around parasite eggs in the liver was greater i...

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Detalhes bibliográficos
Main Authors: Seki, Takenori, Kumagai, Takashi, Kwansa-Bentum, Bethel, Furushima-Shimogawara, Rieko, Anyan, William K., Miyazawa, Yuuki, Iwakura, Yoichiro, Ohta, Nobuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255664/
https://ncbi.nlm.nih.gov/pubmed/22038918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05581-11
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