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Alternative conformations at the RNA binding surface of the N-terminal U2AF(65) RNA recognition motif

The essential pre-mRNA splicing factor, U2 Auxiliary Factor 65KD (U2AF(65)) recognizes the polypyrimidine tract (Py-tract) consensus sequence of the pre-mRNA using two RNA recognition motifs (RRMs), the most prevalent class of eukaryotic RNA binding domain. The Py-tracts of higher eukaryotic pre-mRN...

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Bibliografiska uppgifter
Huvudupphovsmän: Thickman, Karen R., Sickmier, E. Allen, Kielkopf., Clara L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828206/
https://ncbi.nlm.nih.gov/pubmed/17188295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.11.077
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