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Influence of Hyperglycemia on Oxidative Stress and MMP-9 Activation After Focal Cerebral Ischemia/Reperfusion in Rats: Relationship to Blood-Brain Barrier Dysfunction

BACKGROUND AND PURPOSE: Hyperglycemia is linked to a worse outcome after ischemic stroke. Among the manifestations of brain damage caused by ischemia are blood-brain barrier (BBB) disruption and edema formation. Oxidative stress and matrix metalloproteinase-9 (MMP-9) activation are implicated in BBB...

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Hlavní autoři: Kamada, Hiroshi, Yu, Fengshan, Nito, Chikako, Chan, Pak H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828129/
https://ncbi.nlm.nih.gov/pubmed/17272778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.STR.0000258041.75739.cb
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