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A Prospective Assessment of the Y402H Variant in Complement Factor H, Genetic Variants in C-reactive Protein, and Risk of Age-Related Macular Degeneration in Men

BACKGROUND: Two biologically related factors, complement factor H (CFH) and C-reactive protein (CRP) have been associated with age-related macular degeneration (AMD). The Y402H variant of CFH is located within the binding site of CFH for CRP. Although plasma CRP levels have been related to AMD, and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schaumberg, Debra A., Christen, William G., Kozlowski, Piotr, Miller, David T., Ridker, Paul M., YL Zee, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828123/
https://ncbi.nlm.nih.gov/pubmed/16723442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-1456
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