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A Prospective Assessment of the Y402H Variant in Complement Factor H, Genetic Variants in C-reactive Protein, and Risk of Age-Related Macular Degeneration in Men

BACKGROUND: Two biologically related factors, complement factor H (CFH) and C-reactive protein (CRP) have been associated with age-related macular degeneration (AMD). The Y402H variant of CFH is located within the binding site of CFH for CRP. Although plasma CRP levels have been related to AMD, and...

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Detalhes bibliográficos
Main Authors: Schaumberg, Debra A., Christen, William G., Kozlowski, Piotr, Miller, David T., Ridker, Paul M., YL Zee, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828123/
https://ncbi.nlm.nih.gov/pubmed/16723442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-1456
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