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DOES THE SIGNAL FOR THE ACTIVATION OF T CELLS ORIGINATE FROM THE ANTIGEN-PRESENTING CELL OR THE EFFECTOR T-HELPER?
The present view is that the Antigen-Presenting Cell (APC) processes and presents simultaneously on its surface several different antigens that are displayed randomly (with respect to their being Self or Nonself) as peptide-MHC complexes. The naive T-cell interacting with its ligand on the APC is ac...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2006
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1828112/ https://ncbi.nlm.nih.gov/pubmed/16963007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2006.07.010 |
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