Functional Cloning and Characterization of a Multidrug Efflux Pump, MexHI-OpmD, from a Pseudomonas aeruginosa Mutant

We isolated mutant YM644, which showed elevated resistance to norfloxacin, ethidium bromide, acriflavine, and rhodamine 6G, from Pseudomonas aeruginosa YM64, a strain that lacks four major multidrug efflux pumps. The genes responsible for the resistance were mexHI-opmD. Elevated ethidium extrusion w...

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Autores principales: Sekiya, Hiroshi, Mima, Takehiko, Morita, Yuji, Kuroda, Teruo, Mizushima, Tohru, Tsuchiya, Tomofusa
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC182609/
https://ncbi.nlm.nih.gov/pubmed/12937010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.9.2990-2992.2003
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