Functional Cloning and Characterization of a Multidrug Efflux Pump, MexHI-OpmD, from a Pseudomonas aeruginosa Mutant

We isolated mutant YM644, which showed elevated resistance to norfloxacin, ethidium bromide, acriflavine, and rhodamine 6G, from Pseudomonas aeruginosa YM64, a strain that lacks four major multidrug efflux pumps. The genes responsible for the resistance were mexHI-opmD. Elevated ethidium extrusion w...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Sekiya, Hiroshi, Mima, Takehiko, Morita, Yuji, Kuroda, Teruo, Mizushima, Tohru, Tsuchiya, Tomofusa
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Mechanisms of Resistance
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182609/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12937010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2990-2992.2003
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