Aerosolized Cidofovir Is Retained in the Respiratory Tract and Protects Mice against Intranasal Cowpox Virus Challenge

We employed a murine model to test the concept of using an aerosolized, long-acting antiviral drug to protect humans against smallpox. We previously showed that a low dose of aerosolized cidofovir (HPMPC [Vistide]) was highly protective against subsequent aerosolized cowpox virus challenge and was m...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Roy, Chad J., Baker, Robert, Washburn, Kenneth, Bray, Mike
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936997/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2933-2937.2003
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