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A genetic model defines the importance of the atrial natriuretic peptide receptor (guanylyl cyclase-A) in the regulation of kidney function

Disruption of the atrial natriuretic peptide (ANP) receptor [guanylyl cyclase-A (GC-A)] gene yields mice with a salt-resistant form of hypertension, raising fundamental questions on the role of ANP in acute regulation of the kidney. Here, we show that water intake, food consumption, stool weight, ur...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Dubois, Susan K., Kishimoto, Ichiro, Lillis, Terence O., Garbers, David L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18248/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10760303/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.8.4369
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