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Sequence-specific modification of genomic DNA by small DNA fragments

Small DNA fragments have been used to modify endogenous genomic DNA in both human and mouse cells. This strategy for sequence-specific modification or genomic editing, known as small-fragment homologous replacement (SFHR), has yet to be characterized in terms of its underlying mechanisms. Genotypic...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Gruenert, Dieter C., Bruscia, Emanuela, Novelli, Giuseppe, Colosimo, Alessia, Dallapiccola, Bruno, Sangiuolo, Federica, Goncz, Kaarin K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182219/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12952908/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI19773
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