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Sequence-specific modification of genomic DNA by small DNA fragments
Small DNA fragments have been used to modify endogenous genomic DNA in both human and mouse cells. This strategy for sequence-specific modification or genomic editing, known as small-fragment homologous replacement (SFHR), has yet to be characterized in terms of its underlying mechanisms. Genotypic...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC182219/ https://ncbi.nlm.nih.gov/pubmed/12952908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319773 |
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