Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

To determine the relationship between cerebral Glc metabolism and glutamatergic neuronal function, we used (13)C NMR spectroscopy to measure, simultaneously, the rates of the tricarboxylic acid cycle and Gln synthesis in the rat cortex in vivo. From these measurements, we calculated the rates of oxi...

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Bibliographic Details
Main Authors: Sibson, Nicola R., Dhankhar, Ajay, Mason, Graeme F., Rothman, Douglas L., Behar, Kevin L., Shulman, Robert G.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC18211/
https://ncbi.nlm.nih.gov/pubmed/9419373
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