Distinctive role of Stat3 and Erk-1/2 activation in mediating interferon-γ inhibition of TGF-β(1) action

Interferon-γ (IFN-γ) is a multi-functional cytokine that elicits antifibrotic activity in a variety of organs. In this study, we investigated the potential role and mechanism of IFN-γ in modulating the fibrogenic action of transforming growth factor (TGF)-β(1) in tubular epithelial cells. Incubation...

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Hlavní autoři: Giannopoulou, Myrto, Iszkula, Steven C., Dai, Chunsun, Tan, Xiaoyue, Yang, Junwei, Michalopoulos, George K., Liu, Youhua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1821083/
https://ncbi.nlm.nih.gov/pubmed/16332928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00388.2005
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