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Inhibition of Proinflammatory RANTES Expression by TGF-β1 Is Mediated by Glycogen Synthase Kinase-3β-dependent β-Catenin Signaling

TGF-β1 is a pleiotropic cytokine with potent anti-inflammation property. However, the mechanisms underlying TGF-β1 suppression of inflammation remain largely unexplored. In this study, we demonstrated that TGF-β1 inhibited TNF-α- or IL-1-induced RANTES expression in human kidney tubular epithelial c...

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Detalhes bibliográficos
Main Authors: Dai, Chunsun, Wen, Xiaoyan, He, Weichun, Liu, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044962/
https://ncbi.nlm.nih.gov/pubmed/21189258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.174821
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