Nalaganje...

Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase

Because of their low asparagine synthetase (ASNS) expression and asparagine biosynthesis, acute lymphoblastic leukemia (ALL) cells are exquisitely sensitive to asparagine depletion. Consequently, asparaginase is a major component of ALL therapy, but the mechanisms regulating the susceptibility of le...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Iwamoto, Shotaro, Mihara, Keichiro, Downing, James R., Pui, Ching-Hon, Campana, Dario
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1821067/
https://ncbi.nlm.nih.gov/pubmed/17380207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30235
Oznake: Označite
Brez oznak, prvi označite!