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Mad3p, a pseudosubstrate inhibitor of APC(Cdc20) in the spindle assembly checkpoint
Inappropriate attachment/tension between chromosomal kinetochores and the kinetochore microtubules activates the spindle assembly checkpoint, which delays anaphase by blocking the ubiquitin-mediated degradation of securin/Pds1p by APC(Cdc20). The checkpoint proteins Mad2 and Mad3/BubR1 bind to Cdc20...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820940/ https://ncbi.nlm.nih.gov/pubmed/17369399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1511107 |
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