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Kinetic diversity in G-protein-coupled receptor signalling

The majority of intracellular signalling cascades in higher eukaryotes are initiated by GPCRs (G-protein-coupled receptors). Hundreds of GPCRs signal through a handful of trimeric G-proteins, raising the issue of signal specificity. In the present paper, we illustrate a simple kinetic model of G-pro...

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Detalhes bibliográficos
Main Authors: Katanaev, Vladimir L., Chornomorets, Matey
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820807/
https://ncbi.nlm.nih.gov/pubmed/16989639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060517
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