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Endogenous IL-12 triggers an antiangiogenic program in melanoma cells
The IL12RB2 gene acts as a tumor suppressor in human B cell malignancies. Indeed, Il12rb2 knockout (KO) mice develop spontaneously B cell tumors, but also lung epithelial tumors. This latter phenotype may be related to (i) impairment of host IL-12-mediated immunosurveillance and/or (ii) IL-12 inabil...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820697/ https://ncbi.nlm.nih.gov/pubmed/17360466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609028104 |
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