IL-12 Can Target Human Lung Adenocarcinoma Cells and Normal Bronchial Epithelial Cells Surrounding Tumor Lesions

BACKGROUND: Non small cell lung cancer (NSCLC) is a leading cause of cancer death. We have shown previously that IL-12rb2 KO mice develop spontaneously lung adenocarcinomas or bronchioalveolar carcinomas. Aim of the study was to investigate i) IL-12Rβ2 expression in human primary lung adenocarcinoma...

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Main Authors: Airoldi, Irma, Di Carlo, Emma, Cocco, Claudia, Caci, Emanuela, Cilli, Michele, Sorrentino, Carlo, Sozzi, Gabriella, Ferrini, Silvano, Rosini, Sandra, Bertolini, Giulia, Truini, Mauro, Grossi, Francesco, Galietta, Luis Juan Vicente, Ribatti, Domenico, Pistoia, Vito
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702099/
https://ncbi.nlm.nih.gov/pubmed/19582164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006119
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