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Systematic genome instability screens in yeast and their potential relevance to cancer

To systematically identify genes that maintain genome structure, yeast knockout mutants were examined by using three assays that followed marker inheritance in different chromosomal contexts. These screens identified 130 null mutant strains exhibiting chromosome instability (CIN) phenotypes. Differe...

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Hlavní autoři: Yuen, Karen W. Y., Warren, Cheryl D., Chen, Ou, Kwok, Teresa, Hieter, Phil, Spencer, Forrest A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820685/
https://ncbi.nlm.nih.gov/pubmed/17360454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610642104
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