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Gallium (III) triflate catalyzed efficient Strecker reaction of ketones and their fluorinated analogs

The synthesis of α-aminonitriles and their fluorinated analogs has been carried out in high yield and purity by the Strecker reaction from the corresponding ketones and amines with trimethylsilyl cyanide using gallium triflate in dichloromethane. Monofluoro-, difluro-, or trifluoromethyl groups can...

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Hlavní autoři: Prakash, G. K. Surya, Mathew, Thomas, Panja, Chiradeep, Alconcel, Steevens, Vaghoo, Habiba, Do, Clement, Olah, George A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820647/
https://ncbi.nlm.nih.gov/pubmed/17360416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611316104
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