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Gallium (III) triflate catalyzed efficient Strecker reaction of ketones and their fluorinated analogs

The synthesis of α-aminonitriles and their fluorinated analogs has been carried out in high yield and purity by the Strecker reaction from the corresponding ketones and amines with trimethylsilyl cyanide using gallium triflate in dichloromethane. Monofluoro-, difluro-, or trifluoromethyl groups can...

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Autors principals: Prakash, G. K. Surya, Mathew, Thomas, Panja, Chiradeep, Alconcel, Steevens, Vaghoo, Habiba, Do, Clement, Olah, George A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820647/
https://ncbi.nlm.nih.gov/pubmed/17360416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611316104
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