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Selective Requirements for E2f3 in the Development and Tumorigenicity of Rb-Deficient Chimeric Tissues
The tumor suppressor function of the retinoblastoma protein pRB is largely dependent upon its capacity to inhibit the E2F transcription factors and thereby cell proliferation. Attempts to study the interplay between pRB and the E2Fs have been hampered by the prenatal death of Rb; E2f nullizygous mic...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820513/ https://ncbi.nlm.nih.gov/pubmed/17210634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01854-06 |
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