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A Triple Helix within a Pseudoknot Is a Conserved and Essential Element of Telomerase RNA
Telomerase copies a short template within its integral telomerase RNA onto eukaryotic chromosome ends, compensating for incomplete replication and degradation. Telomerase action extends the proliferative potential of cells, and thus it is implicated in cancer and aging. Nontemplate regions of telome...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820488/ https://ncbi.nlm.nih.gov/pubmed/17210648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01826-06 |
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