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A Triple Helix within a Pseudoknot Is a Conserved and Essential Element of Telomerase RNA

Telomerase copies a short template within its integral telomerase RNA onto eukaryotic chromosome ends, compensating for incomplete replication and degradation. Telomerase action extends the proliferative potential of cells, and thus it is implicated in cancer and aging. Nontemplate regions of telome...

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Detalhes bibliográficos
Main Authors: Shefer, Kinneret, Brown, Yogev, Gorkovoy, Valentin, Nussbaum, Tamar, Ulyanov, Nikolai B., Tzfati, Yehuda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820488/
https://ncbi.nlm.nih.gov/pubmed/17210648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01826-06
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