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LRIG1 Is a Novel Negative Regulator of the Met Receptor and Opposes Met and Her2 Synergy

The Met receptor tyrosine kinase regulates a complex array of cellular behaviors collectively known as “invasive growth.” While essential for normal development and wound repair, this program is frequently co-opted by tumors to promote their own growth, motility, and invasion. Met is overexpressed i...

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Autori principali: Shattuck, David L., Miller, Jamie K., Laederich, Melanie, Funes, Melanie, Petersen, Heidi, Carraway, Kermit L., Sweeney, Colleen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820466/
https://ncbi.nlm.nih.gov/pubmed/17178829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00757-06
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