Effect of ketoconazole on isolated mitochondria from Candida albicans.

Ketoconazole, an oral antimycotic imidazole drug, blocked the transport of electrons in the respiratory chain of Candida albicans under aerobic conditions with different substrates, such as NADH and succinate. This effect was a nonspecific inhibition of NADH oxidases and succinate oxidases. The addi...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Shigematsu, M L, Uno, J, Arai, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1982
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182046/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6287930/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.6.919
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