Effect of ketoconazole on isolated mitochondria from Candida albicans.

Ketoconazole, an oral antimycotic imidazole drug, blocked the transport of electrons in the respiratory chain of Candida albicans under aerobic conditions with different substrates, such as NADH and succinate. This effect was a nonspecific inhibition of NADH oxidases and succinate oxidases. The addi...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Shigematsu, M L, Uno, J, Arai, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1982
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182046/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6287930/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.6.919
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