Effect of ketoconazole on isolated mitochondria from Candida albicans.

Ketoconazole, an oral antimycotic imidazole drug, blocked the transport of electrons in the respiratory chain of Candida albicans under aerobic conditions with different substrates, such as NADH and succinate. This effect was a nonspecific inhibition of NADH oxidases and succinate oxidases. The addi...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Shigematsu, M L, Uno, J, Arai, T
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1982
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182046/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6287930/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.6.919
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