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Tetrahymena POT1a Regulates Telomere Length and Prevents Activation of a Cell Cycle Checkpoint

The POT1/TEBP telomere proteins are a group of single-stranded DNA (ssDNA)-binding proteins that have long been assumed to protect the G overhang on the telomeric 3′ strand. We have found that the Tetrahymena thermophila genome contains two POT1 gene homologs, POT1a and POT1b. The POT1a gene is esse...

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Bibliografiske detaljer
Main Authors: Jacob, Naduparambil K., Lescasse, Rachel, Linger, Benjamin R., Price, Carolyn M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820449/
https://ncbi.nlm.nih.gov/pubmed/17158924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01975-06
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