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Tetrahymena Pot2 Is a Developmentally Regulated Paralog of Pot1 That Localizes to Chromosome Breakage Sites but Not to Telomeres

Tetrahymena telomeres are protected by a protein complex composed of Pot1, Tpt1, Pat1, and Pat2. Pot1 binds the 3′ overhang and serves multiple roles in telomere maintenance. Here we describe Pot2, a paralog of Pot1 which has evolved a novel function during Tetrahymena sexual reproduction. Pot2 is u...

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Foilsithe in:Eukaryot Cell
Main Authors: Cranert, Stacey, Heyse, Serena, Linger, Benjamin R., Lescasse, Rachel, Price, Carolyn
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2014
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248686/
https://ncbi.nlm.nih.gov/pubmed/25303953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00204-14
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