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Essential Role of Insulin and Insulin-Like Growth Factor 1 Receptor Signaling in Cardiac Development and Function

Cardiovascular disease is the leading cause of death in people with type 2 diabetes and is linked to insulin resistance even in the absence of diabetes. Here we show that mice with combined deficiency of the insulin receptor and insulin-like growth factor 1 (IGF-1) receptor in cardiac and skeletal m...

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Détails bibliographiques
Auteurs principaux: Laustsen, Palle G., Russell, Steven J., Cui, Lei, Entingh-Pearsall, Amelia, Holzenberger, Martin, Liao, Ronglih, Kahn, C. Ronald
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820447/
https://ncbi.nlm.nih.gov/pubmed/17189427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01110-06
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