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S-Adenosyl-L-methionine: macrocin O-methyltransferase activities in a series of Streptomyces fradiae mutants that produce different levels of the macrolide antibiotic tylosin.

A series of mutants of Streptomyces fradiae selected for increased production of the macrolide antibiotic tylosin was analyzed for levels of expression of macrocin O-methyltransferase, the enzyme which catalyzes the final step in the biosynthesis of tylosin. Increased tylosin production was accompan...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Seno, E T, Baltz, R H
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1982
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182007/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7103455/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.5.758
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